It is a problem for diabetics patients that measuring blood glucusis requires penetrating the skin up to six times every day, in order to inject the correct amount of insulin.

I suggest a combination of an ear sticker and an e-patch, for practical, continous blood sugar monitoring.

It is generally ethically accepted to punch a small hole in the ear lobe. We need to place a small blood sugar electrode permanently in the hole, with a micro connector to make connection to an e-patch behind the ear. The surface of the electrode should be bio compatible in order to avoid any allergic reaction. The intention is to let the blood vessels develop an intimate bond with the electrode over several weeks in order to achieve consistent blood sugar measurements. This would help many diabetics to become less dependant of hospital staff and more self supported in terms of optimizing the correct amount of insulin to inject during the day.

Kind regards

Henrik Kofoed

cand.scient.med

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Replies to This Discussion

A personal note.
Of course and luckily things are different to day than they were 30 years ago. Both my grandparents on my fathers side had diabetes. I remember my grandma injecting herself insulin with reusable syringes which she carefully boilled and thereby sterilized. She had diabetes since she was about 50 and died age 82, no visible complications, except laser treatment to the eyes. At the time there was no no long term blood sugar indicator and her actual blood sugar was tested at her family doctor every once in a while. She was an independent kind of lady and every now and then indulged herself in forbidden cream cake and controlled the consequences with insulin. Somehow she. like every other diabetic, (except the teenage ones who cannot yet interpret their symptoms)" knew" approximately what her blood sugar was and acted accordingly.
Hello Pia Koch
Thank you for your note. I am sure treatment of teenage diabetics is more challenging due to less predictable life style, less healthy and cheaper meals and less accuracy on eating times during the day. If you can not have an automatic insulin pump I believe the electronic patch could give the needed continuous blood sugar information feed back to each user. Each type of meal and drinks gives a certain response in blood sugar level, so after a while the user can determine the best time to inject as well as the best amount. The hospital can make statistical results on the collected blood sugar data in order to suggest at different type of insulin (slow or fast dissolving types) for each person.
Do you know of insulin in pill form, is that made possible? If possible, this could take away the more or less painful injection part too. Instead you could simply count up a number of small insulin pills in order to get the right amount, and discretely eat them just before the meal.
Are you aware of any research lab working on your idea, or are you member of such a research group?
Regards,

Reuven Granot, Perlis Ltd
All I know is there are running developments of the electronic patch, and I am trying to come up with new applications of the e-Patch as such. There are already exsisting and economical methods to analyze the blood sugar from a drop of blood. The integration of the sensor in the e-Patch is a question of production technology, I am sure my employer DELTA could achieve this in cooperation with partners. So the real challenge is to proove that the skin can accept the close contact with the reagents, over extended periods (e.g. seven days).
Coloplast has expertise in that area, which of course you know since your are collaborating. From a practical point of view it depends on the reagents and the individual constitution of the skin over time.Most people tolerate the most common clinically proved materials ( trials) well, but after some time conditions change, skin changes due to age or other factors and you need to shift the product or sometimes find another solution.

PS: To a former comment. Oral antidiabetics have existed quite a while now and are suitibale for type2 or mixed forms. As for my grandma I do not know if she was a misdiagnosed and mistreated type 2, but I doubt it.





Henrik Kofoed said:
All I know is there are running developments of the electronic patch, and I am trying to come up with new applications of the e-Patch as such. There are already exsisting and economical methods to analyze the blood sugar from a drop of blood. The integration of the sensor in the e-Patch is a question of production technology, I am sure my employer DELTA could achieve this in cooperation with partners. So the real challenge is to proove that the skin can accept the close contact with the reagents, over extended periods (e.g. seven days).

Hello Reuven Granot

 

You asked about other research labs working on the subject of non invasive blood sugar measuring. I have found one which seems serious/promising about this challenge; the name is  

GrooveInstruments.com

and they are producing a portable device with optical sensor in contact with the skin on a fingertip.

Regards Henrik Kofoed

Reuven Granot said:

Are you aware of any research lab working on your idea, or are you member of such a research group?
Regards,

Reuven Granot, Perlis Ltd

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